Molecular Biology
Molecular biology is the branch of biology that deals with the formation, structure, and function of macromolecules essential to life, such as nucleic acids and proteins, and especially with their role in cell replication and the transmission of genetic information. It is also the branch of biology that deals with the manipulation of DNA so that it can be sequenced or mutated. If mutated, the DNA is often inserted into the genome of an organism to study the biological effects of the mutation.
Using transformed or mutated cell lines that contain specific gene sequences has become an important component to understanding cell function and disease, and ultimately developing new drugs. There are numerous methods available to examine cellular responses to various compounds that may activate apoptosis, cause cell cycle disruption, and death. But, researchers are always looking for more sensitive, reproducible, yet cost-effective methods for performing these studies.
Guava Systems, with a variety of turnkey functional assays, including optimized reagents and, in most cases, assay-specific acquisition and analysis software, offer an easer and more cost-effective alternative to traditional laboratory methods. The built-in 96-well microplate and tube sample format found in many Guava Systems makes it convenient to test many different transfected cell lines and conditions at once. In addition, the blue laser, featured in Guava EasyCyte Systems, allows for excitation of green fluorescent protein (GFP), a common biological marker for assessing transfection efficiencies of your genetically coupled target protein.
In today’s molecular biology laboratory, flow cytometry technologies are a valuable tool for studying genetic information in the context of cells.
For more information about how a Guava System can support your molecular biology research efforts, please visit the following links:
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