Cancer
Cancer is the second leading cause of death in the United States and represents about 13% of all deaths worldwide. It may affect people at all ages, but risk for the more common varieties tends to increase with age.
Cancer is a disease characterized by a population of cells that grow and divide without respect to normal limits, invade and destroy adjacent tissues, and may spread to distant anatomic sites. Nearly all cancers are caused by abnormalities in the genetic material of the transformed cells. These abnormalities may be due to the effects of the environment, such as exposure to carcinogens, or cancer-promoting genetic abnormalities which may be inherited, and thus present in all cells from birth.
Complex interactions between carcinogens and the host genome make it a challenging task for researchers to understand its underlying mechanism of action and find cures for the many forms of this disease. Thus, it is important for researches to have tools that allow them to easily study cancerous cells and their affects under varying biological conditions: for instance, cancerous cells bypass the natural process of programmed cell death or apoptosis. Also, some genes may have control over the cell cycle, thus encouraging or preventing unwanted cell growth.
Guava Technologies provides optimized turnkey assays for apoptosis, cell cycle, and antigen expression, which are highly relevant to cancer research. Each assay is easy, cost-effective, and sensitive. The Guava® Apoptosis Assays provide easy assessment of very early, early, mid, and late apoptotic effects. And, the Guava Express® Assay allows for user-defined studies to explore unique proteins. Finally, the Guava® Cell Cycle Assay provides an easier alternative to traditional methods for monitoring the various stages of the cell cycle.
For more information about how a Guava System can support your cancer research, please visit the following links:
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