BioProcessing
One of the biggest bottlenecks in drug discovery is the production of the biological material, taking anywhere from one-quarter to one-third of the 10-15 year process required to bring a drug to market. Identifying the correct cell line in which to create the protein or biodrug, assessing the best media conditions for cell growth in different bioreactor sizes, ensuring efficacy and potency of the protein during the scale-up process, developing quality control methods to monitor production, all make optimizing bioreactor conditions a challenging task.
Guava Systems, with their optimized reagents and assay-specific software modules, provide an easier, more cost-effective, and sensitive alternative to traditional methods, such as conventional flow cytometry or microscopy. Each Guava System delivers single-cell analysis, and many feature built-in 96-well plate and tube sample inputs, making it convenient to test many different cell lines and media conditions at a single time. In addition, the blue laser featured in the Guava EasyCyte Systems allows for excitation of green fluorescent protein (GFP), a common biological marker for assessing transfection efficiencies of your genetically coupled target protein.
Truly the easiest, automated, single-cell analysis system on the market, Guava Microcapillary Flow Cytometers lend themselves nicely to quality control, where testing of product against established cellular parameters affords a more sensitive alternative to population-based methods.
For more information about how a Guava System can support your bioprocessing efforts, please visit the following links:
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